The objective of this study is to evaluate the safety and effectiveness of a new investigational biologic product for the management of canine atopic dermatitis. You will be invited to participate in this study if your dog meets all eligibility requirements. If you choose to participate, your dog will be screened free of charge to confirm it meets the criteria for this study. Once enrolled in the study, your dog will receive physical exams and either a study drug, or placebo, at no cost to you, and you can earn up to $150 for your dog’s participation. You will be asked to perform skin assessments at scheduled visits. You will also be asked to bring your dog to the clinic once a week for up to eight weeks.