The objective of this study is to evaluate the safety and effectiveness of a new investigational biologic product for the management of canine atopic dermatitis. Pet owners will be invited to participate in this study if their dog meets all eligibility requirements. Participants will be screened free of charge to confirm they meet the criteria for this study. Once enrolled in the study, the patient will receive physical exams and either a study drug, or placebo, at no cost. Pet owners will be asked to perform skin assessments at scheduled visits and asked to bring the patient to the clinic once a week for up to eight weeks.